It 268 years ago, 25 April 1751, when Timothy Isham and Rebecca Fuller were married in Bolton, Connecticut.  They were my 6 times great grandparents.

Timothy Isham was born 30 May 1725 in Barnstable, Massachusetts, to Isaac and Abigail Lumbert Isham.   He died 16 July 1812 in Bolton.   Rebecca Fuller was born 3 April 1731, also in Barnstable, Massachusetts to Samuel and Lydia Conant Fuller.   Rebecca was a direct descendant of Mayflower passengers Edward Fuller and Samuel Fuller.  Rebecca died 8 March 1823 in Bolton, Connecticut.

The couple had 16 children: Thankful (1752) [my 5 times great grandmother], Abigail (1753), Timothy (1755), Joseph (1756), Benjamin (1758), Rebecca (1759), Temperance (1761), Ebenezer (1762), Samuel (1764). David (1767), Daniel (1767), Joshua (1769), Anna (1771), Elizabeth (1772), Isaac (1774), and John (1776)!